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Thread: Baby Born With HIV 'Cured': Guyana-born Johns Hopkins

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    Registered User Seawall's Avatar Seawall is offline
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    Baby Born With HIV 'Cured': Guyana-born Johns Hopkins

    Congrats Doctor Persaud!


    Baby Born With HIV 'Cured': Guyana-born Johns Hopkins Virologist Persaud
    Written by Demerara Waves
    Tuesday, 05 March 2013 07:00


    Dr. Deborah Persaud of Johns Hopkins' Children's Center in Baltimore, Maryland. (Johns Hopkins Medicine photo)
    (ASSOCIATED PRESSS).-A baby born with the AIDS virus appears to have been cured, a research team headed by Dr. Deborah Persaud announced March 3, describing the case of a child from Mississippi who's now 2 and a half and has been off medication for about a year with no signs of infection.
    India-West reported that Persaud, born in Guyana Aug. 23, 1960, moved to Brooklyn, New York when she was a teenager. Of Indian heritage, she earned her B.A. from York College, M.D. degree from NYU Medical School, and did her pediatric residency at Columbia-Presbyterian. She was the only recipient of the Elizabeth Glaser Pediatric AIDS Foundation’s 2005 Scientist Award, which included a $700,000 research grant.
    There's no guarantee the child will remain healthy, although sophisticated testing uncovered just traces of the virus' genetic material still lingering. If so, it would mark only the world's second reported cure.
    Specialists say the March 3 announcement, at a major AIDS meeting in Atlanta, offers promising clues for efforts to eliminate HIV infection in children, especially in AIDS-plagued African countries where too many babies are born with the virus.
    "You could call this about as close to a cure, if not a cure, that we've seen," Dr. Anthony Fauci of the National Institutes of Health, who is familiar with the findings, told the Associated Press.
    A doctor gave this baby faster and stronger treatment than is usual, starting a three-drug infusion within 30 hours of birth. That was before tests confirmed the infant was infected and not just at risk from a mother whose HIV wasn't diagnosed until she was in labor.
    "I just felt like this baby was at higher-than-normal risk, and deserved our best shot," Dr. Hannah Gay, a pediatric HIV specialist at the University of Mississippi, said in an interview.
    That fast action apparently knocked out HIV in the baby's blood before it could form hideouts in the body. Those so-called reservoirs of dormant cells usually rapidly reinfect anyone who stops medication, said Persaud, associate professor of pediatrics and director of the Infectious Disease Fellowship Program at Johns Hopkins’ Children’s Center in Baltimore, Maryland.
    She led the investigation that deemed the child "functionally cured," meaning in long-term remission even if all traces of the virus haven't been completely eradicated.
    Next, Persaud's team is planning a study to try to prove that, with more aggressive treatment of other high-risk babies. "Maybe we'll be able to block this reservoir seeding," virologist Persaud said.
    No one should stop anti-AIDS drugs as a result of this case, Fauci cautioned.
    But "it opens up a lot of doors" to research if other children can be helped, he said. "It makes perfect sense what happened."
    Better than treatment is to prevent babies from being born with HIV in the first place.
    About 300,000 children were born with HIV in 2011, mostly in poor countries where only about 60 percent of infected pregnant women get treatment that can keep them from passing the virus to their babies. In the United States, such births are very rare because HIV testing and treatment long have been part of prenatal care.
    "We can't promise to cure babies who are infected. We can promise to prevent the vast majority of transmissions if the moms are tested during every pregnancy," Gay stressed.
    In the Mississippi case, the mother had had no prenatal care when she came to a rural emergency room in advanced labor. A rapid test detected HIV. In such cases, doctors typically give the newborn low-dose medication in hopes of preventing HIV from taking root.
    But the small hospital didn't have the proper liquid kind, and sent the infant to Gay's medical center. She gave the baby higher treatment-level doses.
    The child responded well through age 18 months, when the family temporarily quit returning and stopped treatment, researchers said. When they returned several months later, remarkably, Gay's standard tests detected no virus in the child's blood.
    Ten months after treatment stopped, a battery of super-sensitive tests at half a dozen laboratories found no sign of the virus' return. There were only some remnants of genetic material that don't appear able to replicate, Persaud said.
    In Mississippi, Gay gives the child a check-up every few months: "I just check for the virus and keep praying that it stays gone."
    The mother's HIV is being controlled with medication and she is "quite excited for her child," Gay added.

    "Every onlooker is either a coward or a traitor." — Frantz Fanon

    “If there is no struggle, there is no progress. Those who profess to favor freedom, and yet depreciate agitation, are men who want crops without plowing up the ground. They want rain without thunder and lightning. They want the ocean without the awful roar of its many waters.” Frederick Douglass

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    Who feels it knows it! Georgeflash's Avatar Georgeflash is offline
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    I don't believe it.
    Say no to drugs.
    Smoke weed.

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    Move Quick...Doh Stick TRINILI0N's Avatar TRINILI0N is offline
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    I believe that there are cures for almost every disease out there. The dont want to cure ... they will only surppress these illnesses. Im sure they said "fock that shyt" at one point in time ... Bun Babylon ...
    Linkage !!!

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    Sagattarius notorious saga's Avatar notorious saga is offline
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    Cure = 0000000
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    dreadman likes this.
    Man ah Barbeerian bound tuh be by de bar beer in meh hand beastly cold.

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